METABOLIC DISORDERS IN ADOLESCENTS WITH ARTERIAL HYPERTENSION, FACTORS OF PROGRESIV

Authors

  • L. Bohmat SI “Institute for Children and Adolescents Health Care of the NAMS of Ukraine”, Kharkiv
  • N. Shevchenko V.N. Karazin Kharkiv National University
  • V. Nikonova SI “Institute for Children and Adolescents Health Care of the NAMS of Ukraine”, Kharkiv
  • I. Bessonova SI “Institute for Children and Adolescents Health Care of the NAMS of Ukraine”, Kharkiv
  • E. Akhnazariants SI “Institute for Children and Adolescents Health Care of the NAMS of Ukraine”, Kharkiv

Keywords:

blood lipid spectrum, endothelial dysfunction, carbohydrate and purine metabolism

Abstract

282 adolescents with arterial hypertension were examined. An increase in body mass index was accompanied by an increase in the frequency of dyslipidemias, disorders of carbohydrate and purine metabolism, the development of endothelial dysfunction (according to vasodilation tests), an increase in the levels of endothelin-I and inflammation factors (C-reactive protein, IL-6, TNF-α), microalbuminuria. This information can be the basis for identifying among adolescents with arterial hypertension of persons in need of longterm dispensary observation with control of lipid profile, carbohydrate and purine metabolism, and correction of therapy.

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Published

2021-10-20

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Abstract