INDICATORS OF FREE RADICAL OXIDATION AND ANTIOXIDANT PROTECTION IN ADOLESCENTS WITH HYPOANDROGENISM

Abstract

In adolescents with hypoandrogeny (HA), an imbalance is recorded in the ratio of the processes of free radical oxidation (FRO) and antioxidant protection (AOP). In a third of patients, the concentration of TBA-active products increases, in half of them, the level of carbonylated proteins and the coefficient of oxidative stress increases and the activity of anti-peroxide enzymes decreases. The results indicate the formation of oxidative stress in boys with HA, the main initiator of which is the inhibition of the AOP system.